What medicine should be taken for reflux esophagitis?
Reflux esophagitis (GERD) is a common digestive system disease caused by inflammation caused by the reflux of gastric acid into the esophagus. Patients often present with symptoms such as heartburn, chest pain, and difficulty swallowing. Medication for reflux esophagitis is one of the main methods. Based on the hot topics and patient concerns on the Internet in the past 10 days, this article has compiled a detailed medication guide.
1. Classification of commonly used drugs for reflux esophagitis
| drug type | Representative medicine | Mechanism of action | Applicable people |
|---|---|---|---|
| Proton pump inhibitors (PPIs) | Omeprazole, pantoprazole, rabeprazole | Inhibit gastric acid secretion and reduce esophageal irritation | Patients with moderate to severe reflux |
| H2 receptor antagonist | ranitidine, famotidine | Block histamine receptors and reduce gastric acid secretion | Mild symptoms or adjuvant treatment |
| Antacids | Aluminum magnesium carbonate, aluminum hydroxide | Neutralizes stomach acid and quickly relieves symptoms | Temporary use during acute attacks |
| Gastrointestinal motility drugs | Domperidone, Mosapride | Accelerate gastric emptying and reduce reflux | People with gastric insufficiency |
2. Drug selection and precautions
1.Proton pump inhibitors (PPIs): It is currently the most effective acid-suppressing drug and is suitable for long-term symptom control. However, it should be noted that long-term use may cause osteoporosis or vitamin B12 deficiency. Regular review is recommended.
2.H2 receptor antagonist: Suitable for combined use when acid breakthrough occurs at night or when PPI is ineffective, but the long-term effect is not as good as PPI.
3.Antacids: It has a quick onset of action, but the effect is short-lived and should not be relied upon for a long time. Aluminum-containing preparations may cause constipation and need to be adjusted with diet.
4.Gastrointestinal motility drugs: Suitable for patients with delayed gastric emptying, but avoid taking it with anticholinergic drugs.
3. Answers to recent hot questions
According to patient discussions in the past 10 days, the following issues have received high attention:
| Popular questions | Expert advice |
|---|---|
| "Can I take omeprazole for a long time?" | The recommended course of treatment is 4-8 weeks, and long-term use requires physician evaluation. |
| “What should I do if the reflux continues to occur after taking medicine?” | Check the triggers (such as diet, obesity) and use combined medications if necessary. |
| “How to choose medicine for reflux in pregnant women?” | Prefer magnesium aluminum carbonate and avoid PPI (unless necessary). |
4. Lifestyle Assisted Treatment
Drug treatment needs to be combined with lifestyle adjustments:
-diet: Avoid high-fat, spicy and caffeinated foods and eat small meals frequently.
-body position: Fasting 3 hours before going to bed and raising the head of the bed 15-20 cm.
-lose weight: Obese patients need to control their BMI and reduce abdominal pressure.
Summary: The choice of drugs for reflux esophagitis needs to be determined based on the severity of symptoms and individual differences. It is recommended to standardize medication under the guidance of a doctor and cooperate with lifestyle improvements to achieve the best effect.
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